Les groupes sanguins érythrocytaires (2e édition)

To meet the challenge of immunological transfusion safety, this book offers a comprehensive overview of current data in immunohematology, presenting the different human erythrocyte blood group systems and the basis of their polymorphism. This 2nd edition incorporates recent developments (9 new systems since the previous edition) and the latest genomic innovations.

• System by system, the fundamentals are developed: the history of discovery, classification of antigens and phenotypes, genes and gene diversity, membrane and tissue distribution of antigens, and the antibodies that recognize them.

• Each chapter also covers the links between phenotypes and pathologies, the sensitivity of antigens to enzymatic treatments and their clinical involvement in autoimmunity phenomena.

• The authors then review cross-cutting aspects such as HLA antigens, poly-agglutinability, frequency variability, genetic anthropology...

This didactically designed book is intended for hematologists, biologists and transfusionists, as a tool for meeting the challenges posed by blood transfusion. For the specialized reader, it provides answers to the majority of questions concerning erythrocyte blood group antigens and genes.