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A detailed summary of the molecular mechanisms involved.
Identifying the angiogenesis players has paved the way for the birth of regenerative medicine! The practical spin-off effects of these discoveries are considerable for both tumour (anti-angiogenic strategy) and ischaemic (restoring a functional vascular bed) diseases.
How do we stimulate and create good quality vessels in a territory under distress?
Different approaches are explored to increase angiogenesis in human disease, and tactics based on molecular and cellular events that arise in cases of ischaemia.
This exhaustive book offers, in a detailed and illustrated way :
- A review of the molecular and cellular mechanisms implicated in vascular regeneration (hypoxia, inflammation, hormones…)
- A analysis of the main clinical trials in gene or cell therapy in a critical way