Immune thrombocytopenic purpura and other autoimmune cytopenias

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Pages: 176
Format: 170X240
ISBN : 978-2-7420-0770-7
Printed in: French
Publication date: 01/07/2011

Book written in french

The pathophysiology of autoimmune thrombocytopenic purpura (the most common form of autoimmune cytopenia) and autoimmune haemolytic anaemias is still poorly understood, and their treatment is mainly based on the recommendations of experts.

Certain refractory autoimmune cytopenias require specialised management of patients with the most severe forms, as well as access to new molecules (biotherapies).

At the dawn of this therapeutic revolution, a monograph on autoimmune cytopenias was needed to update the knowledge of doctors (clinicians as well as biologists) in haematology: better understanding of the pathophysiology, an assessment of current therapeutic advances, improvement in the management of patients.

This training book addresses in a practical and pedagogical manner the diagnosis and treatment of the main forms of autoimmune cytopenia: Immune thrombocytopenic purpura, haemolytic anaemias and erythroblastopenias, either isolated or in combination with other pathologies (lymphoid blood diseases, connective tissue diseases, immune deficiencies, infections).

Conceived as a guide, this summary will interest a broad audience of doctors, specialised or not in haematology, such as internal medicine doctors and immunologists. This practical work is also intended for hospital pharmacists and intensive care practitioners.

CONTENTS:

- Immune thrombocytopenic purpura

Epidemiology of ITP
Pathophysiology of ITP
Diagnosis of immunological purpura in adults and children
When to suspect constitutional thrombocytopenia in assessing thrombocytopenia in children and adults
When to consider medicinal treatment in the context of thrombocytopenia that appears to be autoimmune in nature
Treatment of ITPin children and adults
ITP and pregnancy

- Autoimmune haemolytic anaemia

Pathophysiology of AHAI
Diagnosis and
therapeutic management of
AHAI in children and adults
Chronic disease
of cold agglutinins

- Other autoimmune cytopenias

Autoimmune neutropenias
Erythroblastopenias
Erythroblastopenias associated with agents stimulating erythroblastopoiesis
Autoimmune cytopenias and lupus
Infections and autoimmune thrombopenias
Autoimmune cytopenias
and lymphoproliferative diseases
Immune deficiencies and autoimmune cytopenias